TS420 Perivascular Flow Module

Precision Volume Flow Measurements for In Vivo Animal Studies

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Precision Volume Flow Measurements for In Vivo Animal Studies

Transonic® is the recognized gold standard for blood flow measurement in animal studies and physiological research. The TS420 Perivascular Flow Module provides unprecedented waveform quality and accuracy. A complete line of Perivascular Flowprobes is available for small and large vessel sizes and for acute use and chronic implantation.

The TS420 Perivascular Flow Module for in vivo use incorporates the plug & play features that researchers have come to expect from Transonic’s high quality scientific instruments. Known for their reliability, Transonic Flow Modules are virtually maintenance-free.

Transonic TS420 Perivascular Flow Modules fit into 400-Series Instrumentation Consoles and are compatible to mix and match with other 400-Series Modules.

Typical Applications

  • Small Animal Cardiovascular; Even Mice!
  • Renal Hypertension Studies
  • Carotid Occlusion Thrombosis Models
  • Large Animal Cardiovascular
  • Exercise Physiology, Heart Failure Models, Pregnancy Research, Myocardial Ischemia & Reperfusion
  • VAD Implantation & Heart Assist Models
  • Novel Species: Comparative Physiology

 

Compatible Flowprobes (0.5 – 36 MM)

  • PR / PS / V-Series Flowprobes & Nanoprobes
  • PAU-Series COnfidence Flowprobes® for Cardiac Output and great vessels
  • PMP-Series – Handle style Flowprobes for acute intraoperative applications

 

Support Documents

TTU VOLUME FLOW TECH NOTE: Keys to Accurate Perivascular Flow Measurements with Transit-Time Ultrasound
PUB BRIEF (Abu-Gazala) Status of Adult Living Donor Liver Transplantation in the United States: Results from the Adult-To-Adult Living Donor Liver Transplantation Cohort Study

General Features

Size 5.125” h x 4” w x 9.062” d

Weight: 2.2 lbs.

Module fits 2 Console slots (20HP) in T402 or T403 Consoles

Power: Derives input power from 400-Series Consoles. Installation in a Console is required.

 

Operational Technology

Ultrasonic Transit-time

 

Flowprobe Compatibility

PS-, V-, PR-, PMP- & PAU-Series

 

Probe Connector

Front panel 10-pin connector. Accepts research perivascular Flowprobes and extension cables with male CRA 10-pin connectors.

 

Automatic Adjustments

Probe size identification and corresponding flow output ranges. Volume flow calibration of applied Probe.

 

Digital Display

4-Digit (14 segment) LED displays Flow / Probe data / Error Messages

Bar Indicator Light: Displays received signal amplitude for continuous monitoring of Probe signal quality

 

Analog Display

Taut-band needle (-0.2 volts to +1.2 volts ) displays Flow / Received Signal Amplitude/Calibration information

 

Zero Adjust

Recessed momentary push button to zero flow reading at stopped flow

 

Mode Button Controls

Select modes of operation of displays and outputs

  • MEASURE MODE: Displays current volume flow values. Indicator light bar shows received signal strength
  • TEST MODE: Displays Probe size & received signal amplitude
  • ZERO MODE: Sets outputs to zero flow to calibrate external recording device
  • SCALE MODE: Sets outputs to scale factor flow to calibrate external recording device

 

Low Range

Low Range increases flow gain by a factor of 4

 

Filter Properties

  • 1, 10, 40 Hz: 2nd order Butterworth, with a third passive pole at 160 Hz
  • 160 Hz: 3rd order Butterworth

 

Invert

Invert the polarity of analog flow outputs and flow displays

 

Signal Outputs

8 accessible signals via 400-Series Flowmeter Console’s back-panel terminal block: Pulsatile Volume Flow; Mean Volume Flow, Received Signal Amplitude (2); Phase (4)

 

Ultrasonic Frequency Range

600 KHz to 14.4 MHz; Probe size dependent

 

Flow Output

Front panel mounted BNC output connector & rear panel terminal block:

  • Pulsatile/Average Volume Flow
  • Filtering controlled by front panel selectable filters
  • Voltage range: -5 to + 5 volts
  • Output resistance: 500 Ohm
  • Full Range for Flow: -5 to +5 V (bidirectional flows, with range of 5 x scale factor flow)

 

Automatic Digital Probe ID & Calibration

TS420 circuitry reads Probe operational data (size, scale & calibration) programmed in the probe’s EPROM.

  • Probes with 10 or 12-pin connectors: EPROM installed in the connector.
  • 4-pin Probe connectors require separate EPROM keys

CAL KEY PORT: Front panel socket accepts 3-pin EPROM calibration keys for Flowprobes with 4-pin connectors. Flowmeter reads and uses “CAL KEY” data if both a separate calibration key and connector EPROM are present.

 

Synchronization

Rear panel jumpers select synchronization mode

  • Self-Triggering Mode: “SYNC IN” to “SYNC OUT” jumper on each Module
  • Sequential Triggering Mode: “SYNC IN” crossed to “SYNC OUT” between Modules

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