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Forced Running Wheels
Defined Exercise Schedules
Forced Running Wheels are designed for controlled exercise studies and for sleep deprivation applications. We provide standard wheels with 250mm diameter for rats (80mm depth) and 115mm diameter for mice (40mm depth). For larger rats special drums with 160mm depth are available. When used in sleep deprivation studies the front lids can be equipped with an integrated holder to fix a drinking bottle and a food trough.
For testing fine motor skills and motor learning the wheel drum can be equipped with easily removable rods to change the rod pattern between sessions. If camera observation is required during the test the front of the wheel is made from clear material so that paw usage of the animal is easily visible.
All wheels are equipped with an electronically-controlled motor that guarantees reliable and consistent speed that is adjustable up to 60rpm. If only constant speed is required throughout the experiment the manually operated wheel is a cost-effective solution. Speed and rotation direction are set manually for each wheel, the current speed is shown on an integrated display on the motor control.
For maximum convenience, the wheels can be connected to a computer (USB connection). The Active Running Wheel software package allows to freely define speed profiles individually for each wheel – up to 100 steps can be combined, each step with duration, initial speed, final speed – use continuous mode with extra-slow speed, alternate active and pause phases or define acceleration or decelerating speed ramps for controlled exercise applications.
When combined with TSE PhenoMaster Indirect Calorimetry the forced running wheel can be used to examine the relationship between exercise and energy expenditure (CaloWheel).
Features
- Wheels for rats and mice
- Easily removable drum
- Motor skill wheels with adjustable rod spacing
- Manual or PC controlled configuration
- Changeable rotation direction
- Speed up to 60rpm – 50m/min rat, 22m/min mouse
- Programmable speed profiles
Applications
- Forced Exercise
- Sleep Deprivation
- Stress Induction
Disease Models
- Diabetes
- Obesity
- Parkinson´s
- Stress
- Stroke
Compatible with
Selected Publicatons:
Marti, AR, Pedersen TT, Wisor JP et al. Cognitive function and brain plasticity in a rat model of shift work: role of daily rhythms, sleep and glucocorticoids. Sci Rep 2020; 10: 13141
Marti AR, Meerlo P, Grønli J, Van Hasselt SJ, Mrdalj J, Pallesen S, Pedersen TT, Henriksen TEG, Skrede S. Shift in food intake and changes in metabolic regulation and gene expression during simulated night-shift work: A rat model. Nutrients 2016; 8(11): 712.
Selected Product Citations
Cognitive function and brain plasticity in a rat model of shift work: role of daily rhythms, sleep and glucocorticoids |
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| Andrea R Marti, Torhild T Pedersen, …, Janne Grønli | Sci Rep | Published 4 Aug 2020 |
| Article Snippet tivity for 8 h per day, centred either in their normal active phase (active work; ZT14–22) or in their normal rest phase (rest work; ZT2–10), as described previously 11, 17, 35. Animals were placed in automatically rotating wheels (Rat Running Wheel,TSE Systems, Homburg, Germany,24 cm diameter; 3 rpm; 1,440 revolutions or approx. 1.1 km of linear distance per 8-h session). Food and water were available ad libitum. Rotating wheels, feeders and water bottles were cleaned after each work session wi |
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Shift in Food Intake and Changes in Metabolic Regulation and Gene Expression during Simulated Night-Shift Work: A Rat Model |
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| Andrea Rørvik Marti, Peter Meerlo, …, Silje Skrede | Nutrients | Published 08 Nov 2016 |
| Article Snippet Abstract: Night-shift work is linked to a shift in food intake toward the normal sleeping period, and to metabolic disturbance. We applied a rat model of night-shift work to assess the immediate effects of such a shift in food intake on metabolism. Male Wistar rats were subjected to 8 h of forced activity during their rest (ZT2-10) or active (ZT14-22) phase. Food intake, body weight, and body temperature were monitored across four work days and eight recovery days. Food intake gradually shifted toward rest-work hours, stabilizing on work day three |
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Low-carbohydrate high-fat diets in combination with daily exercise in rats: effects on body weight regulation, body composition and exercise capacity. |
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| Samantha J Caton, Maximilian Bielohuby, …, Martin Bidlingmaier | Physiol Behav | Published 9 Feb 2012 |
| Article Snippet Abstract: The aim of the current investigation was to examine the effects of consuming a low-carbohydrate high-fat diet (LC-HFD) in combination with daily exercise on body weight, body composition, endocrine control of the energy balance system and exercise capacity in adolescent and mature rats.. Adolescent (n=23) and mature rats (n=16) were maintained on either a standard chow diet (CH) or a LC-HFD for a period of ten days prior to daily exercise training for 21 days in forced running wheel system. |
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