RFLSI-ZW Laser Speckle Contrast Imaging System
RFLSI-ZW laser speckle imaging system is an even better tool for microcirculation research based on laser speckle contrast imaging technology (LSCI).
With the advanced optical design and improved image processing algorithm, RFLSI-ZW shows greater performance in imaging field size, image quality, full-field frame rate and optical resolution, and provides a powerful and efficient means for human and animal tissue microcirculation measurement.
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Overview
The RFLSI-ZW laser speckle contrast imaging system utilises LSCI technology, the advantages of which are its non-contact, high frame-rate, high spatial resolution. The system can be used to observe and record blood perfusion of any exposed tissues or organs for microcirculation study or pre-clinical researches like ischemic stroke, lower limbs, mesentery, etc. Multi-Output includes blood perfusion images and videos (500+ million pixels), quantified data for perfusion unit and vessel diameter.
Since 2019, the RFLSI-ZW laser speckle contrast imaging system has been adopted by more than 100 colleges, universities, and research institutes worldwide such as Stanford University School of Medicine, university of manchester, UC Davis, Duke university. What’s more, it has contributed to publishing more than 60 reputed research papers in magazines like Nature communications, Blood, Diabetes, and Theranostic.
Applications
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Cerebral blood perfusion monitoring
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MCAO model assessment
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Cortical spreading depression observation
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Hind-limb ischemia research
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Skin burn/skin flap transplantation
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Organ microcirculation observation
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Skin allergies
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Septic Shock
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Chicken Chorioallantoic Membrane Assay
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Diabetic Foot
Highlights Of RFLSI-ZW
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Image any exposed tissue (skin or surgically exposed tissues) and species.
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Non-contact, non-contrast agent depending measurement.
- The built-in CMOS global shutter camera can achieve faster data acquisition and processing speed.
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Best optical resolution of 3.9 μm/pixel, providing more detailed tissue structures.
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Max frame rate (full field) up to 100 fps, acquiring real-time changes in larger areas.
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Motorised 10x optical zoom and auto focus. Image size ranges from 0.57×0.75 to 22.5×30 cm2 in all-in-one imager, covering multiple research applications.
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Fast auto and fine manual focus, improving focus efficiency and accuracy on various tissues.
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Optimal lens assembly, filtering the ambient and reflecting light.
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Class 1 of measurement and indicating lasers, safe to use without eye protection System
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Laser stability hardware for the ultimate in reliable and consistent measurement over minutes, hours and days.
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Calibration with calibration box. Self-calibration is possible at any time to keep the equipment in optimal working condition.
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Trigger In/Out BNC connections for communication with external devices.
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Unlimited installation of analysis software in PC.
| Resolution | Max Camera Resolution：2064×1544 pixels Best Resolution：3.9 μm/pixel |
| Image | Flux/Gray/Intensity/Color/Overlay |
| Measurement Laser | 785 nm, Class 1 |
| Indicating Laser | 650 nm×2, Class 1 |
| Focus | Auto/Manual (fine focus) |
| Trigger | 2×BNC |
| Image Size | 0.57× 0.75-22.5×30 cm2 |
| Max Frame Rate | 100 FPS (full field) |
| Zoom | 10× |
| Working Distance | 10-40 cm, continuous |
| System Calibration | Calibration Box |
| Measurement Algorithms | Temporal and Spatial processing |
| Pc Connections | 1 x USB 3.0 port |
| Software | Acquisition Software and Analysis Software |
| Power Supply | Universal Voltage, 100V-230V. Note acquisition rate is unaffected by frequency of local electrical supply. |
| Stand Options | Scan head has standard VESA mount for desktop stand, Microstand and Clinical Mobile stand. |